American Board of Surgery Qualifying Exam (ABS QE) Practice Test

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What is the source of inferior parathyroid glands?

  1. 2nd pharyngeal pouch

  2. 3rd pharyngeal pouch

  3. 4th pharyngeal pouch

  4. Thymus gland

The correct answer is: 3rd pharyngeal pouch

The inferior parathyroid glands originate from the third pharyngeal pouch during embryonic development. In the early stages of embryogenesis, the pharyngeal apparatus differentiates into various structures, including the parathyroid glands. Specifically, the third pharyngeal pouch gives rise to both the inferior parathyroid glands and the thymus gland. This anatomical relationship is important as it highlights the developmental pathways of these structures and their position within the neck region. The inferior parathyroid glands are specifically located near the lower pole of the thyroid gland, while the thymus is positioned more anteriorly in the mediastinum. Understanding the embryological origins of these glands is crucial for grasping their anatomical relationships and potential clinical implications, such as in cases of congenital abnormalities or during surgical procedures involving the thyroid and parathyroid glands. The other choices relate to different structures without connection to the inferior parathyroid glands. The second pharyngeal pouch forms the palatine tonsils, while the fourth pharyngeal pouch is responsible for the development of the superior parathyroid glands and the ultimopharyngeal body, which contributes to the formation of part of the thyroid gland. The thymus gland, though derived from